Attend any lecture about dry eye and you will hear the “I” word, inflammation. It is well established that dry eye is an inflammatory condition. How about contact lens wear?
Ocular inflammation during contact lens wear is associated with serious complications such as microbial keratitis, however, there may be more subtle inflammatory mechanisms.  In a January 2017 publication, the authors propose that contact lens wear is intrinsically inflammatory and examined whether uncomplicated contact lens wear meets the classical and the contemporary clinical definitions of inflammation. The classical definition consists of rubor (redness), calor (heat), tumor (swelling), dolor (pain) and functio laesa (loss of function). Cellular and biochemical reactions define the contemporary, sub-clinical definition of inflammation.
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